4 Tests Performed During Colon Cancer Screenings

March 8, 2025

Regular screenings, such as a colonoscopy, play a significant role in detecting colon cancer in its early stages. These screenings can identify abnormalities in the colon or rectum that may suggest the potential for cancerous growths. Several tests are available for colon cancer screenings, each offering unique methods for examining the body and detecting signs of concern. Here is some information about four commonly used tests in colon cancer screenings.

1. Colonoscopy 

Doctors commonly use a colonoscopy to identify colon-related concerns. During this test, a medical professional inserts a thin, flexible tube called a colonoscope into the rectum. The colonoscope’s camera allows them to examine the entire colon and rectum for abnormalities such as polyps, inflammation, or other irregularities.

If unusual tissues or polyps are found during the procedure, they can often be removed immediately for analysis. A colonoscopy offers a complete view of the colon, making it a valuable diagnostic tool. It is often recommended as a follow-up to other screening tests that detect irregularities.

2. Fecal Immunochemical Test (FIT) 

The fecal immunochemical test (FIT) is a non-invasive screening method. It is designed to detect traces of blood in stool, which may indicate colon cancer or precancerous conditions. Patients collect a stool sample at home using a collection kit provided by their healthcare provider and return the sample for laboratory analysis.

FIT is convenient because it requires no preparation or dietary restrictions. It is often used as an initial screening tool for adults at average risk of colon cancer. If a FIT result is positive, further diagnostic procedures like a colonoscopy may be recommended to identify the source of the bleeding.

3. CT Colonography 

A CT colonography, also called a virtual colonoscopy, is a minimally invasive imaging test. It uses a CT scanner to capture detailed pictures of the colon and rectum. These images help healthcare providers detect polyps, tumors, or other abnormalities without using an internal camera.

Before the test, patients may need to follow a specific preparation routine to clear the bowels. During the procedure, a small tube introduces air or carbon dioxide into the colon to expand it, making it easier to capture clear images. CT colonography is a useful option for those unable to undergo a traditional colonoscopy, though it may require follow-up testing if abnormalities are identified.

4. Stool DNA Test

The stool DNA test, also known as a multitarget stool DNA test or Cologuard, is another non-invasive screening option that combines the detection of blood in stool with an analysis of DNA markers linked to colon cancer or precancerous polyps. Patients collect a stool sample at home using a kit provided by their healthcare provider and send it to a lab for analysis. This test is convenient and does not require bowel preparation or dietary restrictions, making it an appealing option for many. If abnormalities are detected, a follow-up colonoscopy may be needed for further evaluation.

Understanding Screening Options 

Colon cancer screenings provide individuals with different options to monitor their health. They help people take proactive steps to address potential concerns. Each screening method has unique characteristics. Healthcare providers can guide patients in choosing the best test based on personal risk factors, medical history, and preferences. By understanding the available tests, patients can feel more confident and comfortable with colon cancer screenings.

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